Roundworms helped open a new extension mechanism for youth
Aging can be seen as a natural process or as a logical development of the organism during its life cycle. However, mankind throughout its history tried to find "the cure for eternal youth" or at least, as much as possible (to the extent possible) to delay the onset of old age. And, quite possibly, the answer all the time was, you might say, "under our feet." Indeed, recently a group of researchers from the University of Michigan discovered in roundworms special substance that prevents aging.
As you know, roundworms (nematodes) are one of the most numerous species on the planet. They have very different size and are found in soil, as well as fresh and marine waters, where their number may exceed 1 million individuals per 1 cubic meter.
By studying one species of these animals, namely, C. elegans, scientists have found, you can say "aging molecule". At first, experts from the University of Michigan studied the change in mobility of worms associated with age. It turned out that in the middle of the life cycle of animals coming decline of physical activity. On average, C. elegans live for about 21 days, and somewhere in the 10-11 day there is a change in behavior. Scientists decided to find out the cause of these disorders. Experts have begun to analyze the connection of motor neurons with muscle activity. It was found that their interaction gives SLO-1 molecule. When its presence and activity decline occur gradual extinction motor functions. Accordingly, the SLO-1 is greater, the less activity.
Further, the experts decided to try to block this molecule. To do this, they used a 2 way lock (Looking ahead to say that both were successful). The first - the most "radical". Blocking a molecule at the genetic level by editing the genome. The second - the impact on the "way" interaction molecules. With the help of paxillin scientists blocked the potassium channels involved in the allocation of SLO-1.
Moreover, the lifespan of the test groups increased compared with the control. But the interesting thing is that the opening applies not only to nematodes as well as a similar molecule in the body, there are other creatures (including mammals).
Incidentally, it is proved that to maintain "the mind of youth," you should always learn something new. For this ideal, our news channel Telegram.